Verospiron 25mg Tablet

✔️ Uses of Verospiron 25mg Tablet

• Heart failure
• High blood pressure (hypertension)
• Edema (swelling) caused by various conditions
• Treatment of low potassium levels in the body (hypokalemia)

✔️ How does Verospiron 25mg Tablet work?

Verospiron is a potassium-sparing diuretic that lowers blood pressure and reduces swelling by eliminating excess water and electrolytes without causing potassium loss.

✔️ Side Effects of Verospiron 25mg Tablet

Nausea, Vomiting, Leg cramps, Dizziness, Drowsiness, Confusion, Breast enlargement in males, Increased creatinine level in blood.

✔️ Quick Suggestions:

• May cause dizziness initially; avoid activities requiring concentration.
• May increase potassium levels; avoid potassium supplements and potassium-rich foods.
• Regularly monitor kidney function, potassium levels, and blood pressure.
• Report dizziness, diarrhea, vomiting, swelling in feet, or difficulty breathing to the doctor.

✔️ Indication

Hypertension, Edema, Hypokalemia, Hepatic cirrhosis with ascites and edema, Hyperaldosteronism, Severe congestive heart failure.

✔️ Pharmacology

• Spironolactone, the active ingredient, is a specific pharmacologic antagonist of aldosterone.
• Acts by binding to receptors at the aldosterone-dependent sodium-potassium exchange site.
• Causes increased sodium and water excretion while retaining potassium.

✔️ Dosage & Administration:

• Varied dosages based on the specific condition being treated.
• Adjustments may be made according to the patient's response.
• Regular monitoring of kidney function and potassium levels is essential.
• Should be taken with food. Taking it early in the day can reduce the need to wake up at night for frequent urination.

✔️ Interaction

• ACE inhibitors: Concomitant use may lead to severe hyperkalemia.
• Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur.
• Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur.
• Lithium: High risk of lithium toxicity.
• Digoxin: Verospiron increases the half-life of digoxin.

✔️ Contraindications

Anuria, Hyperkalemia, Acute or progressive renal insufficiency, Addison's disease.

✔️ Pregnancy & Lactation

Use in pregnancy and lactation requires careful consideration of potential benefits versus risks.

✔️ Precautions & Warnings

• Patients with kidney problems or difficulty urinating should use Verospiron with caution.
• Lifestyle changes like exercise and a low-salt diet may enhance its effectiveness.
• Avoid alcohol consumption.
• Inform the doctor about kidney, liver, or heart diseases, pregnancy, or other medications being used.
• Pregnant or breastfeeding women should consult their doctor.

✔️ Storage Conditions

• Store in a cool and dry place protected from light.
• Keep out of reach of children.